For its inhibitory activities on cyclo-oxygenase enzyme & PGE synthesis and on hyaluronidase, which contributes significantly to cartilage degradation, and Guggulu as chondroprotective is very effective in different arthritis. It reduces pain & stiffness.
It promotes the synthesis of intracellular triglycerides, lowers its degradation, and thereby reduces the depth of wrinkles, imparting skin glow & a smooth appearance. Guggulu stimulates lipogenesis inside the fibroblasts, leading to better contact with the extracellular protein network and tones up the dermis.
Guggulu is an effective drug in cardiovascular conditions. It inhibits liver cholesterol synthesis, increases lipolytic activity in liver & controls the GI absorption of cholesterol. It significantly lowers the levels of total cholesterol, triglycerides and total lipids.
For its ability to increase WBC to stimulate phagocytosis, Guggulu is useful in the treatment of infection & inflammation. As an anti- infective drug, very useful in the management of acute and chronic conditions like neuro- articular disorders, recurrent infections, ulcers, acne etc.