Kalamegha Ghanavati

155 for 45 T
अथ कालमेघस्तु....................................
सुतिक्तो लघु रूक्षोष्णः कफपित्तविनाशनः ।
दीपनः स्वेदनो ज्ञेयो ज्वरघ्नः कृमिनाशकः ।
यकृद्रोगे कृमौ कुष्ठे ज्वरे चासौ प्रशस्यते ॥१३६॥
Reference: Priya Nighantu, Shatapushpadi Varga, 136
Each tablet contains aqueous extract derived from 2.5 g of Kalamegha (Andrographis paniculata).
Jwara, Krimi, Yakrut roga and Kushta. 
1-2 tablets, 2-3 times a day, one hour before food or as directed by the physician.


Andrographolide, a bitter diterpene lactone found in areal parts, is more potent hepatoprotective than standard drug silymarin. Kālamegha is useful in infective hepatitis & protects from hepatic injury. It improves bile flow.


It is an important and integral part of Ayurvedic antipyretic formulations. Active constituents viz, andrographolide, neoandrographolide & de- hydroandrographolide are attributed with antipyretic and anti-infective properties.


It is a useful adjuvant in management of diabetes. Kālamegha significantly lowers blood sugar, increases plasma insulin, hepatic glycogen, and total haemoglobin. It decreases levels of glycosylated haemoglobin & reduces oxidative stress.


Kālamegha causes significant elevation of catalase, superoxide dismutase & glutathione-s-transferase activities. It inhibits the formation of oxygen derived free radicals, superoxide hydroxyl radicals, lipid peroxidation & nitric oxide.