By its mucoprotective activity, Sariva significantly protects from the formation of gastric and mucosal lesions and heals acid- peptic ulcers. It is a safe and effective drug in the management of hyperchlorhydria.
Sariva alleviate ethanol- induced liver toxicity. It has shown to induce apoptosis in human hepatocellular carcinoma HepG2 cell by caspase-3 and caspase-9 activation, pro-apoptotic Bax up-regulation and anti- apoptotic Bcl-2 genes down- regulation.
It reduces reactive oxygen species (ROS) and inflammatory cytokines IL8 and TNFA(32) and shows anti-inflammatory activity compared to diclofenac sodium gel. Terpenes, sterols, and phenolic compounds show protective activities against arthritis.
Owing to the coolant property, the aqueous extract of Sariva is safe and effective drug in management of Acid peptic disorders, Burning micturition, Burning sensation, Haemorrhoids & Fever.
